Plenty of cartoons were made with characters or things coming right at the audience. It seems that half of the Harman-Ising shorts for Warner Bros. had Bosko or someone running with an open mouth to the camera and “swallowing” it.
Leave it to Tex Avery to do it in reverse in the great “The Blitz Wolf” (1942). Look at the arc on 12 frames.
Animation credits go to Ray Abrams, Irv Spence, Preston Blair and Ed Love.