‘Jumbo Gro’ does its job in Tex Avery’s fan-favourite “King-Size Canary” (1947). The hobo cat pours it in the little bird (Sara Berner). These are consecutive drawings. Note the squash and stretch on the bird.
The bird grows some more.
And a typical Avery extreme in reaction.
Bob Bentley, Ray Abrams and Walt Clinton are the credited animators.